Better Together: OMOP + i2b2
Unlock More Value from OMOP with i2b2
Many institutions have adopted the OMOP Common Data Model to standardize and harmonize clinical data. But once your data is in OMOP, a new question emerges:
How do researchers actually access and use it efficiently? This is where i2b2 complements OMOP.
i2b2 can sit directly on top of your existing OMOP schema, providing a powerful, researcher-friendly interface and ecosystem that enables cohort discovery, feasibility analysis, and governed data access—without disrupting your underlying data model.
Better Together
OMOP and i2b2 serve different but highly complementary roles:
- OMOP standardizes and structures your data
- i2b2 activates that data for researchers
Together, they create a complete, end-to-end research data platform:
- Standardized data → Accessible insights
- Harmonized schema → Usable workflows
- Data infrastructure → Research acceleration
How i2b2 Works with OMOP
i2b2 can be deployed on top of OMOP in multiple ways:
- Direct mappings between OMOP tables and i2b2 ontology structures
- Pre-built transformations that expose OMOP concepts in i2b2’s query interface
- Support for hybrid architectures (OMOP + i2b2 + SHRINE or other federated layers)
This allows institutions to:
- Preserve their OMOP investment
- Avoid duplicative data pipelines
- Provide immediate usability to researchers
Why Use OMOP + i2b2?
Whether you already have OMOP in production or are planning your data platform strategy, i2b2 can help you unlock its full potential.